Have you heard of ProtonDB? It rates the current state of games and recommended fixes.

Gaming on Linux has improved a lot over the years. It’s typically only multiplayer games with Easy Anti-Cheat (EAC) that you’ll run into major issues with. Mod managers frequently require a fair amount of extra work and reading but I think a lot of Bethesda games have easy work arounds and documentation.

They work just fine. You can either attempt to use the install script Lutris provides you and hope it gives you the option to supply your own files (this is primarily GOG games and source ports) or set up a new game from scratch by selecting the exe file of the installer and later changing it to the game.

You should check ProtonDB even if you aren’t using Proton to make sure there’s no additional fixes or edits that need to be applied.

If you need help or have questions let me know.