I love a good impossible burger over a normal burger for the big reason of how I feel after. Eating a normal burger as I am getting older means that I feel full in a gross way after, like I can feel the fat from the burger slowing me down, and I feel tired both physically and mentally and I sometimes feel borderline sick for an hour or so after. But with the impossible burgers I can just feel full in a healthy way. I love it. I will admit to also getting it with bacon though for that extra flavor.

I an pretty anti factory farm and love the idea of cutting out at least burgers from their industry. I also enjoy their sausages. Highly recommend them if you have not tried them. I try to cut out bulk meat eating for the environment and keep it to occasional, smaller portions, and even then it is normally chicken. Impossible meat helps scratch that itch if I want some meat but don’t want to commit to blowing my personal weekly allotment of red meat.

I use windows and have been since I was a kid in a very computer savvy home. Build my first computer at 8 or 9 years old with surplus 80’s parts, ISO slots and all. First OS install was dos with a shell GUI and have had every major windows iteration starting g with 3.1 and up. Of the more modern ones that followed the windows 95 esthetic, I loved windows 2000 pro, hated xp, then loved 7 pro, hated 8, and accepted windows 8.1. When it came to windows 10 I was already getting frustrated with the excessive bloat and OS level Spyware. Now with eindows 11 BIOS level Spyware and so much bloat even the most modern CPUs lag, this is now a bridge too far for me. I will not be upgrading to 11 and will instead be jumping over to Linux. I played around with Linux in the 2000’s and a bit with server stuff, but never took it seriously as a desktop replacement OS until now.

So who are the ‘real’ people switching over? People like me. I don’t work in IT. 99% of my computer usage is for things I can do through a web browser, office suit, or gaming through steam, all of which is now very accessible through Linux. If this was Linux from 10 or 15 years ago, I don’t think you would have seen the shift happen, but where it is at now is more accessible for the common user than ever before.

I miss HEB. family owned and private. Thus why they get away with treating their employees so well, paying them well, and supporting their communities all while also being the largest private employer in the state of Texas. That company is a great example of how a company can both grow to a large size and not be evil. If they ever go public you know all of its charm will instantly get cut in the name of shareholder value.

I knew a guy who swore by swimming goggles for eye dust protection.

I would love it if reddit clamped down on free speech. Please reddit, just lay it out on what else you want to limit. Let the people know what else they can’t say. Or even better- force people on reddit to make mandatory posts praising billionaires. It would make my day. Please reddit, put more gas on your dumpster fire

This article is written with some wild speculations by both the author of the article and the source they are quoting. When cell phones are cracked for evidence they have to use write blockers when they copy the phone. They do the analysis on the copy. The original is then re-copied in court to show what was found. This way the original is never tampered with and made inadmissible, and whatever analysis bullshit you did isn’t mixed in with your court room copy. What this also means is that your AI can hallucinate all it wants and make up any evidence you can imagine all day long, but when you get into the court room and have to then point to where the conclusions came from and you can’t-you will be standing there with a dick on your forehead and with a case being tossed out.

Think of a more direct democracy. I will oversimplify enough to annoy those from Switzerland:

Differing levels of law require differing thresholds. Country votes on a law, the majority above the required threshold vote it in. It becomes a national law. That is easy. What about when it fails? Then look to the state level. Did it pass the threshold for your state? Yes? Then it is a state law. Failed state level? Let’s look at your county/city/local level. Passed threshold? Local law.

Again, over simplified, but general idea.

While I have progressive ideas and believe the Republicans rule with malace, I also strongly believe the democrats rule with incompetence.

I would love to run for president on the party of burn down the two party system and restart from there. Make politics boring again and not some partisan winner take all spectacle. We keep pushing to out ‘wing’ the ‘wing’ and it is driving us to some bad extremes.

So yes, I will vote straight ticket Democrat for 99% of the time, but I am also disgusted by the fact anyone is even allowed to do that and people have little party letters by their name. If you didn’t research your candidate to at least know their name, then you shouldn’t be voting for them.

It is mind-blowing to me that some things are not seen as human rights and are instead seen as political posturing. In Texas we had barbed wire intentionally strung up in the Rio Grande river with the intention to drownd people and it took multiple rounds of court cases to make them take it out. Somehow killing people is acceptable rather than booking, ticketing, and sending back. Politics have now taken a place above literal lives. At the same time, when I express this I have democrats immediately agreeing and adding “just let them in!” Or “just let them stay and we will figure it out” and that is where I stop them and ask, is that what I said? No. Simply that human life is worth more than politics. Again, stringing up barbed wire in a river to intentionally drown people it true malice. But saying let them all in and figure it out later is naive at best, and incompetence at its worst.

Am I the only one who read the paper? All the comments are like: it’s only mice.

They did it in 6 different breeds of knockout mice, rats, and beagles -as in the best dog model for cancer translation to humans. They are well passed the threshold needed to show strong potential in people.

Other comments: it’s new and experimental

They have been working with it for years now and have shown efficacy down to a single dose. That is what this paper is about. They had previous tests with the compound, then with decreasing doses, and now this paper will it down to a single dose.

Other comments: there is no way this is real

Of the 9 primary authors, 4 are on NIH grants. I’m taking a wild guess no one here has had to fill one of those out, but they take about a month of solid writing and submitting evidence as to why your thing should get funded due to the shortage of scientific funding, then it gets reviewed by several rounds of blinded experts in the field to evaluate if you have any merit to what you are talking about, then you have to submit regular updates to show that you aren’t just pissing away tax dollars. On top of that, this was done out of a lab at the university of Illinois urbana-champaign, meaning you also have university funds mixed in so you have them checking in on you. Then they also had a state cancer research grant, adding more oversight.

How real is it? If you read the paper you would have seen they were using human tumors grown in the mice. This is a very well established cancer testing method. The downfall in their model, as they pointed out, is using NSG and athymin mice. These are immunocompromised mice. They bring up how with the necrotic cell death in the tumor (from the drug working ironically so well and so fast) that they don’t know how human immune systems will respond to it and that is kind of their next direction of the research.

Read the full abstract, then at least read the discussion section near the end if you want to get a better understanding of what is going on. Then if you are still interested, go back up to the intro and read through from there till you can’t any more.

Looking passed the absolutely insane answer here, no one has even brought up the whole issue of AC vs DC. Batteries are DC, while your fridge that plugs into your wall running on AC. I know they make DC ones, but it isn’t like they are interchangeable.