Since you need an Digital ID to sign, given by your government, i can’t think of many issues.

e: i just looked since it was a while since i signed - you need to give your Passport number to sign, or use eID.

aaah i misremembered, it was Ted Cruz, oops :-D

https://arstechnica.com/tech-policy/2025/07/ted-cruz-gives-up-on-ai-law-moratorium-joins-99-1-vote-against-his-own-plan/

especially that Abbot Ted Cruz, who brought this one up, voted against it in the end, which is pretty confusing for an european tbh

e: i mean that it’s memeworthy lol

876k now - at this speed it will be done tomorrow, or at latest in 2 days!

they might even be personal PIN numbers for identification!

neither 0451 nor 4510 are even registering, i’m disappointed.

i have it too, and i used it a lot, but most people i knew at that time went for Sony

Most of my friends are women, i have more issues with men than women; and they also aren’t judging when i open up. But i know that they aren’t representative.

The issue is that it only takes one overzealous woman to ruin a mans life in the US: having trouble with cops on the playground, losing a job over social media accusations without proof - at least for the large majority of men. (things are different when we look at people in power, where hard facts aren’t enough to remove them - this enrages me just as much as any woman)

In that way, women are as much an aggressor as men are, it’s just that their tools are different. Where a aggressive man might tend to physical violence, aggressive women are able to dish it out with social violence.

I just wanted to show up that painting men as the source of all evil is shortsighted. There are a lot of women applying pressure to keep men in the role they are in, cementing the patriarchate just as much as men are.

And why shouldn’t they? If you don’t want to work outside of passion projects, or want to be a homemaker while your husband brings in the money? If you shy away from responsibility and feel safer when a strong father figure decides? Or being fine with men being in charge, as long as they have control over their husband? Those lifestyles are all valid too, and they profit directly from the patriarchate in one way or another, even if it might not be healthy at all.

There is no (or next to none) help for men to step outside of this structure. I am totally for helping women to get their rightful place side by side to men, but there also has to be a discussion about how not only men are oppressing everyone, but also how women are using their tools to oppress everyone, and how it is harmful to just paint one side as the perpetrator here.

There also should be more of an discourse about how life and values for men should look after achieving equality, because just replacing the patriarchate with an matriarchate is not gonna cut it.

You know what i see? Men being afraid of going alone with their kid to the park, because the mom’s there believe they are a sexual predator just by gender. Men not appliying for kindergarden or school jobs because of a tendency of mothers to see every man in childcare as a pedophile. Men getting called the cops onto them in the parking lot when going to their car after shopping.

And it’s the same with violence against women - every man is automatically seen as a brutalizer, or someone who would daterape.

As long as those prejudices exist - and they are mainly female prejudices! - men will not open up. When you are seen as a threat even if you aren’t one (see the man and the bear in the woods), there is no way they will become empathic, because innocently playing with your child in the park could have lifelong consequences for you.

Is it really that ridiculous? Biologically seen, men’s properties are mostly due to genetic selection by women over thousands of years, if they are conscious about it or not. Men that are more attractive to women are preferred partners, and the selection pressure is mostly on men, since women have a much higher biological cost in pregnancy, therefore they are much more “picky”. That is pretty proven science, and this pressure is also found in culture: men have the attributes that women want them to have to give them an advantage.

It would only take 2-3 generations of women AND men doing child care to fix those issues by reinforcing openness and acceptance, but that takes education, esp in the human sciences, and education for the masses in the US has been dismantled long ago even before the current razing.

Men’s inability to open up is a trained behavior, and is reinforced the most by the group doing the most child care: women. Everytime a boy that cries gets told to “man up” that stereotype is repeated to them. This produces an echo that reverbs through most of society, and especially children, who then mock peers that express emotions.

Women are training their own oppressors. There is enough blame around for all genders.

Don’t have many bluesky followers, but i made an awareness post - everyone i know and who cares has already signed :-)

for everyone who has an issue with the 30 minuted per run: later on you can speed up the game, so each round is down to 15 minutes.

Alley Cat Remeow Edition is a fan remake of Alley Cat, an arcade game, with up to 4 players, but it’s PC (should still run on that hardware, i hope!)

https://www.youtube.com/watch?v=WIm6oRhyDrM

holy shit! i worked in travel insurance organizing rental cars in case of breakdowns, with hertz as one of our primary partners in some areas, and at least in central europe i didn’t see cases like this. That’s quite shocking to learn for me!

Yeah, my current bluetooth headset has that option, and i keep a cable in reserve. the ones i had to replace were mostly in my teens/tweens, and were still cabled in-ear style - easier to hide under clothes and hair, but also no cable replacing if you don’t know much about how to solder. TBH, if i had to decide i would not go back to cabled headphones at all - it’s simply too limiting and irritating to deal with, especially with multiple audio sources. When listening to music the latency is not important (and has improved a lot in comparison to the humble start), and it’s been a while since i had phones which had sound quality issues because of bluetooth.

I’ve had to swap a lot more cabled headphones out due to cable damage than bluetooth headphones, but i also only use overear headphones, which have enough battery storage for days. Also, there are also overear headsets that are dual-useable with headphone jack or bluetooth (no noise cancelling with jack tho). Also, the issue with the replacement of headphones lies with the producers of headphones w/o changeable power source, not with the phone.

And regarding availability in the US: i have the suspicion that the average european will be much more inclined to pay the 2-300$ upmark in price just for greener tech than the average american. i’m sure that they would love to sell more phones, but it’s not ecological or economical to ship them onto a continent where 80-90% of people would either compare specs only and cannot afford to go for a more sustainable phone or - a predominantly USA thing - who revel in the fact that their choice is not ecological.

No, they are the factories of the cell, building proteins. :-)

from what i remember (it’s been a few years since i studied this stuff lol) you can only arrest the cell cycle (dismantling -> duplication of chromosomes -> separation of chromosomes -> completion of division) at specific points, and can’t go in reverse. Theres a whole cascade of signals, that when started, are running their way to specific checkpoints. if a cell is stuck for too long at any checkpoint, it commits suicide, because that’s THE sign for unrecoverable DNA damage. And if a cell starts ignoring checkpoints and suicide signals, it’s called cancer.

Many antibiotics work that way btw - they look a lot like nucleotides (A C G T), but if a bacterium adds them when copying instead of one of the “letters”, the machinery gets stuck, and the bacterium cant divide anymore. That gives the immune system time to kill them off. Bacteria replicate a lot and have no proofreading of what they are copying, so they are susceptible to this. Animal cells have proofreading AND the ability to correct an error, so we are fine.

I loved studying this stuff. i did NOT love the crapload of chemistry i had to learn, but even that was highly interesting.

You are right (at the 8 cell stage you can still separate them and treat them one at a time, giving you multiple shots at IVF)

Two of the main issues regarding gene editing when not talking single cells are the transfer into the nucleus, and then accessing the DNA you want.

In bacteria, the DNA kinda just swims around in the cell, which makes editing easy if you can get the CRISPR/Cas9 complex in the cell. But animal cells have another membrane surrounding the DNA, making the transfer less than straightforward.

Regarding access: our DNA isn’t lying around like mom’s spaghetti, but rather pretty tightly packed around histones - a protein octamer.

This means that your target might not be reachable (the cell itself has 3 options iirc: slide the DNA over the surface of the histone, replace a part of the histone with an alternative, or remove the histone altogether) Since the way the DNA is wound around the histones affects gene activity (something tightly packed is not active, something in a loose area is getting transcribed into mRNA and therefore possibly active), you cannot just unwind all of it.

The only time this is not the case is during cell division, where the nucleus is getting dismantled so the DNA can be duplicated and both new cells can get their own copy. But many cells do not divide in an adult (except for a reservoir of stem cells which are there to replace lost cells)

So, it’s all very complicated.