Hormones are active in the brain and if you are low it can cause mood problems. Most sources I’ve seen show a 4-5 day half-life for estrodial valerate. This can leave you pretty low before 7 days are up if you are on weekly injections. There are two ways that people typically work around this:
Increasing the dosage high enough that you don’t dip too low. This unfortunately also means that your peak levels may get higher than your Dr is comfortable with.
Splitting the dose in half and injecting two times a week instead of one. This will significantly smooth out the curve, but have the downside of requiring twice the injections.
This is an example simulation with a once weekly 5mg injection vs a twice weekly 2.5mg injection to illustrate the difference between the two:
I guess what I am saying is that there are options if the dosing schedule you start off with causes you problems that you can work through with your Dr. Also, the 5mg I used for the simulation was a semi random number and not a recommended dose.
Hormones are active in the brain and if you are low it can cause mood problems. Most sources I’ve seen show a 4-5 day half-life for estrodial valerate. This can leave you pretty low before 7 days are up if you are on weekly injections. There are two ways that people typically work around this:
This is an example simulation with a once weekly 5mg injection vs a twice weekly 2.5mg injection to illustrate the difference between the two:
I guess what I am saying is that there are options if the dosing schedule you start off with causes you problems that you can work through with your Dr. Also, the 5mg I used for the simulation was a semi random number and not a recommended dose.