I am not someone who follows/has interest in Geo-politics. In lemmy homepage majority of posts are political. Those lemmy’s I do not expect to have political posts in them like c/technology, c/memes, c/lemmyshitposts, their top posts are related to politics. My subscribed, local, and all is full of it. Is there a way to filter them out?

You signed up on one of the most political instances there is. Switch instances and browse Local. Like the other person suggested, lemmy.zip or programming.dev are both good options.
Does this mean I only see comments from the instance I set up an account with?
No, comments are federated, or else I would be almost an island by my self on my instance